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Merck
CN

SAB1404382

Sigma-Aldrich

Monoclonal Anti-SMO, (C-terminal) antibody produced in mouse

clone 1D9, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Gx, SMOH

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1D9, monoclonal

form

buffered aqueous solution

mol wt

antigen ~40.96 kDa

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

NCBI accession no.

NM_005631

UniProt accession no.

Q99835

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SMO(6608)

Immunogen

SMO (NP_005622.1, 653 a.a. ~ 787 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NLWLVEAEISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIPRLPQLPRQKCLVAAGAWGAGDSCRQGAWTLVSNPFCPEPSPPQDPFLPSAPAPVAWAHGRRQGLGPIHSRTNLMDTELMDADSDF

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
07360-1D9
07359-1D9

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Annelies Gonnissen et al.
Oncotarget, 7(51), 84286-84298 (2016-10-08)
Limited data exists regarding the combination of Hedgehog signaling (Hh) inhibition and radiotherapy, even though there are several indications that this might be a promising treatment strategy. In this study, we evaluated the combination of two Hh inhibitors, the SMO

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