SAB1408179
Anti-LOC91461 antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
Synonym(s):
FLJ18197, MGC125960
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~33.3 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SGK493(91461)
Related Categories
General description
Protein kinase domain containing, cytoplasmic homolog (PKDCC) is a secreted protein expressed in platelets. The gene encoding it is localized on human chromosome 2p21. Mouse polyclonal antibody raised against a full-length human LOC91461 protein.
Immunogen
LOC91461 (NP_612379.1, 1 a.a. ~ 294 a.a) full-length human protein.
Sequence
MVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLEKVLHLYRSGQYLQNSTASSSTEYQCIPDSTIPQEDYRCWPSYHHGSCLLSVFNLAEAVDVCESHAQCRAFVVTNQTTWTGRQLVFFKTGWSQVVPDPNKTTYVKASG
Sequence
MVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLEKVLHLYRSGQYLQNSTASSSTEYQCIPDSTIPQEDYRCWPSYHHGSCLLSVFNLAEAVDVCESHAQCRAFVVTNQTTWTGRQLVFFKTGWSQVVPDPNKTTYVKASG
Biochem/physiol Actions
Protein kinase domain containing, cytoplasmic homolog (PKDCC) is crucial for embryonic development. It phosphorylates proteins associated with the endoplasmic reticulum and other secreted proteins. PKDCC has been linked to atopy.
Physical form
Solution in phosphate buffered saline, pH 7.4
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).
Castro-Giner F
BMC Medical Genetics, 10, 128-128 (2009)
A secreted tyrosine kinase acts in the extracellular environment.
Bordoli MR
Cell, 158(5), 1033-1044 (2014)
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