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Merck
CN

SAB2501301

Anti-IDO2 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-INDOL1, indoleamine 2,3-dioxygenase 2

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-IDO2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

canine, bovine, human

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q6ZQW0

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... IDO2(169355)

Related Categories

Biochem/physiol Actions

Indoleamine 2,3 dioxygenase (IDO) 2 plays an important role in the metabolism of tryptophan and in immune regulation. It may participate in B cell-mediated autoimmune diseases. IDO2 is required for IDO1-dependent induction of T regulatory cells (Treg). Removal of IDO2 results in attenuated contact hypersensitivity (CHS) responses.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Indoleamine 2,3 dioxygenase (IDO) 2 is one of the four tryptophan catabolic enzymes in mammals. IDO2 is located on human chromosome 8p21.

Immunogen

Peptide with sequence CRDKTLESILHPR, from the C-Terminus of the protein sequence according to NP_919270.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
9548P1

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Indoleamine-2, 3-dioxygenase (IDO) 2 polymorphisms are not associated with multiple sclerosis in Italians
C Agliardi, et al.
Journal of the Neurological Sciences, 377, 31-34 (2017)
Richard Metz et al.
International immunology, 26(7), 357-367 (2014-01-10)
IDO2 is implicated in tryptophan catabolism and immunity but its physiological functions are not well established. Here we report the characterization of mice genetically deficient in IDO2, which develop normally but exhibit defects in IDO-mediated T-cell regulation and inflammatory responses.

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