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Merck
CN

SAB2702324

Monoclonal Anti-CARD12 antibody produced in mouse

clone GT1387, affinity isolated antibody

Synonym(s):

AIFEC, CARD12, CLAN, CLAN1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
GT1387, monoclonal
Application:
western blot
Species reactivity:
human
Citations:
Technique(s):
western blot: 1:1000-1:10000
Uniprot accession no.:
Q9NPP4

Key Documents

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Product Name

Monoclonal Anti-CARD12 antibody produced in mouse, clone GT1387, affinity isolated antibody

biological source

mouse

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

GT1387, monoclonal

form

buffered aqueous solution

mol wt

116kDa

species reactivity

human

concentration

1mg/mL

technique(s)

western blot: 1:1000-1:10000

isotype

IgG2a

UniProt accession no.

Q9NPP4

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... NLRC4(58484)

Application

Suggested starting dilutions are as follows: WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM]

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human CARD12.

Other Notes

Purification: Affinity purified by Protein A

Physical form

Phosphate-buffered saline, no preservative added.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
41855

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