biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
Influenza A virus subtype H1N1 (swine)
concentration
1 mg/mL
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Swine H1N1 Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2′-5′OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
Immunogen
NS1 antibody was raised against a synthetic peptide from the swine-Origin Influenza NS1.The immunogen is located within the last 50 amino acids of Swine H1N1 Nonstructural Protein 1.
Application
NS1 antibody can be used for the detection of the NS1 protein from the H1N1 strain of Swine-Origin Influenza A in ELISA.
Physical form
Supplied in PBS containing 0.02% sodium azide.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable