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NACRES:
NA.41
UNSPSC Code:
12352203
Technique(s):
immunofluorescence: 5-10 μg/mL using using HeLa cells, immunoblotting: 1-2 μg/mL using using whole extracts of HeLa cells.
Clone:
8E3, monoclonal
Application:
IF
Citations:
2
biological source
rat
Quality Segment
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
8E3, monoclonal
form
buffered aqueous solution
species reactivity
mouse, hamster, rat, bovine, canine, monkey, human
concentration
~1 mg/mL
technique(s)
immunofluorescence: 5-10 μg/mL using using HeLa cells, immunoblotting: 1-2 μg/mL using using whole extracts of HeLa cells.
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
Monkey ... DHX9(715453)
canine ... DHX9(480032)
human ... DHX9(1660)
mouse ... Dhx9(13211)
rat ... Dhx9(304859)
General description
DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) also known as RNA Helicase A, nuclear DNA helicase II (NDHII), belongs to the DExD/H family of helicase superfamily 2, that exhibits both RNA and DNA helicase activity in an ATP dependent reaction.
Immunogen
synthetic peptide corresponding to the N-terminal region of mouse DHX9
Application
Monoclonal Anti-DHX9/RHA antibody produced in rat has been used in immunoblotting and immunofluorescence.
Biochem/physiol Actions
DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) is involved in RNA metabolism including RNA secondary structure rearrangement, RNA-protein interactions, RNA turnover, ribosome biogenesis, translation and small RNA metabolism. It participates in the replication cycles of retroviruses and other RNA viruses. DHX9 is implicated in multiple steps of HIV-1 replication, including transcription, export of unspliced viral RNA from the nucleus, translation, particle assembly and reverse transcription.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 1
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable