SAB4200650
Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse
clone Ep2.17, purified from hybridoma cell culture
别名:
Anti-CNSA1, Anti-EEN, Anti-SH3D2B, Anti-SH3P8
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
Ep2.17, monoclonal
Application:
FACS
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
Ep2.17, monoclonal
form
buffered aqueous solution
mol wt
~41 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
flow cytometry: 2-5 μg/test using using HeLa cells., immunoblotting: 1-2 μg/mL using whole extracts of HeLa.
isotype
IgG2b
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SH3GL1(6455)
General description
Monoclonal Anti-SH3GL1 (C-terminal) (mouse IgG2b isotype) is derived from the hybridoma Ep2.17 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. SH3GL1 (SH3-domain GRB2-like 1), also known as endophilin-A2, is a member of the endophilin family of Src homology 3 (SH3) domain-containing proteins. The SH3 domain drives protein-protein interactions through binding to proline-rich ligands. The SH3GL proteins have a novel N-terminal segment, and a peculiar tissue distribution: SH3GL1 is ubiquitous, SH3GL2 located in the brain, and SH3GL3 in brain and testis.
Immunogen
a synthetic peptide corresponding to a sequence at the C-terminal region of human SH3GL1
Application
Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse has been used in immunoblotting and flow cytometry.
Biochem/physiol Actions
SH3GL1 is involved in several brain tumors, such as glioma, where its levels were increased in proportion to the tumor progression. In cells generated from children malignant brain tumor medulloblastoma (MB), SH3GL1 expression was found to be regulated by the miRNA, miR-218.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable