SAB4300097
Anti-phospho-CDC25C (pSer216) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-CDC25 antibody produced in rabbit, Anti-cell division cycle 25 homolog C (S. pombe) antibody produced in rabbit
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p)
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~60 kDa
species reactivity
human
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200
isotype
IgG
immunogen sequence
(S-P-SP-M-P)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer216)
Gene Information
human ... CDC25C(995)
General description
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclinB-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiplealternatively spliced transcript variants of this gene have been described, however, the full-length nature of many ofthem is not known.
Immunogen
Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P), according to the protein CDC25C.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable