SAB4301078
Anti-TDP2 antibody produced in rabbit
affinity isolated antibody
别名:
AD022, EAP2, EAPII, TTRAP, hTDP2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
4
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
41 kDa
species reactivity
human, mouse
concentration
2.6 mg/mL
technique(s)
immunohistochemistry: 1:50- 1:200, western blot: 1:200-1:1000 (Cell Lysate)
isotype
IgG
accession no.
NP_057698.2
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TDP2(51567)
General description
Tyrosyl DNA phosphodiesterase-2 (TDP2) is a multi-functional protein and is also called as TTRAP (TNF receptor-associated protein). It is a 5′- tyrosyl DNA phosphodiesterase that belongs to the PML NB (promyelocytic leukemia nuclear body) protein family. TDP2 is mapped to human chromosome 6p22.
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human tyrosyl-DNA phosphodiesterase 2
Biochem/physiol Actions
Chromosomal translocations stimulated by DNA topoisomerase II at the time of gene transcription is repressed by tyrosyl DNA phosphodiesterase-2 (TDP2). It is essential to preserve the chromosome stability in human cells. TDP2 participates in cell proliferation, apoptosis and the repair of DNA damage. It promotes cell cycle arrest and apoptosis in osteosarcoma cells.
The antibody detects endogenous levels of total TDP2 protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable