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Merck
CN

SAB4500879

Anti-GPRC6A antibody produced in rabbit

affinity isolated antibody

Synonym(s):

G-protein coupled receptor 33, G-protein coupled receptor family C group 6 member A, GPRC6A, hGPCR33, hGPRC6A

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
3

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 104 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000

NCBI accession no.

Q5T6X5

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GPC6A(222545)

General description

Anti-GPRC6A Antibody detects endogenous levels of total GPRC6A protein.

G protein-coupled receptor class C group 6 member A (GPRC6A) belongs to C G protein-coupled receptors family. It is mapped to human chromosome 6q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human GPRC6A.

Immunogen Range: 471-520

Biochem/physiol Actions

Mutations in G protein-coupled receptor class C group 6 member A (GPRC6A) modulates the activities and expression of cell surface. It also controls prostate cancer progression.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
61321

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Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
J?rgensen S, et al.
The Journal of Biological Chemistry, 292(4), 1524-1534 (2017)
GPRC6A regulates prostate cancer progression
Pi M and Quarles LD
Prostate, 72(4), 399-409 (2012)
Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population
Long QZ, et al.
PLoS ONE, 7(5) (2012)

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