SAB4501602
Anti-JAK2 antibody produced in rabbit
affinity isolated antibody
别名:
JAK-2, JAK2, Janus kinase 2, kinase Jak2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 130 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, immunohistochemistry: 1:50-1:100
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... JAK2(3717)
General description
Anti-JAK2 Antibody detects endogenous levels of total JAK2 protein.
JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the Jak family of proteins. The JAK2 gene is located on human chromosome 9p24.
JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the Jak family of proteins. The JAK2 gene is located on human chromosome 9p24.
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2.
Immunogen Range: 906-955
Immunogen Range: 906-955
Biochem/physiol Actions
JAK2 (janus kinase 2) plays an important role in the activities of cytokine receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable