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Merck
CN

SAB4502683

Anti-p70 S6 Kinase antibody produced in rabbit

affinity isolated antibody

别名:

70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, S6K, S6K1, p70 S6 kinase α

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
4
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 59 kDa

species reactivity

rat, human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPS6KB1(6198)

General description

Ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) belongs to the AGC kinase subfamily and comprises a catalytic domain, a linker region, and a putative autoinhibitory domain, in addition to the N-terminal and C-terminal domain. The RPS6KB1 gene is located on human chromosome 17q23.1. It exists in multiple isoforms due to alternative splice events.

Immunogen

The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase.

Immunogen Range: 195-244

Application

Anti-p70 S6 Kinase antibody produced in rabbit has been used in western blotting (1:1000).

Biochem/physiol Actions

Ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) undergoes acetylation, phosphorylation, and ubiquitination. It is involved in a variety of functions including glucose homeostasis, cell survival, and proliferation. RPS6KB1 also participates in cell structure and organization. It is implicated in ovarian cancer progression, muscle hypertrophy, aging, immunity, and memory. RPS6KB1 also regulates the replication and transcription of mumps virus (MuV).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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