SAB4502977
Anti-KITH, C-Terminal antibody produced in rabbit
affinity isolated antibody
Synonym(s):
KITH, TK-1, TK1, Thymidine kinase, cytosolic
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 25 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TK1(7083)
General description
Anti-KITH Antibody detects endogenous levels of total KITH protein.
The Thymidine kinase 1 (TK1) gene is mapped to human chromosome 17q25.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human KITH.
Immunogen Range: 161-210
Immunogen Range: 161-210
Biochem/physiol Actions
Thymidine kinase 1 (TK1) takes part in the process of DNA synthesis. It catalyzes the formation of pyrimidine deoxynucleotides through salvage pathway. The enzyme is an ATP dependent kinase. TK1 serves as a biomarker, indicating the recurrence of tumor and metastasis of cancer including gastrointestinal cancer, leukemia and lymphoma.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Expression and Clinical Significance of Cytokeratin-19 and Thymidine Kinase-1 in Advanced Gastrointestinal Cancer.
Du YY
Chinese Medical Journal (English Edition), 129(18), 2168-2172 (2016)
Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas.
Heimann P
Cancer Research, 61(10), 4130-4135 (2001)
Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.
D'Costa Z
Cancer Research, 77(21), 5952-5962 (2017)
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