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Merck
CN

SAB4702041

Monoclonal Anti-HLA-DR APC-Cyanine7 produced in mouse

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
APC-Cy7 conjugate
Clone:
L243, monoclonal
Application:
FACS
Citations:
-
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conjugate

APC-Cy7 conjugate

Quality Level

antibody product type

primary antibodies

clone

L243, monoclonal

form

buffered aqueous solution

species reactivity

( Non-human primates), ( Human), dog

technique(s)

flow cytometry: suitable

isotype

IgG2aκ

storage temp.

2-8°C

target post-translational modification

unmodified

General description

HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.

Immunogen

Human B lymphocytes

Biochem/physiol Actions

The mouse monoclonal antibody L243 recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty.

Physical form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB4702041-100TST04065272230728