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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
APC-Cy7 conjugate
Clone:
M38, monoclonal
Application:
FACS
Citations:
-
conjugate
APC-Cy7 conjugate
antibody product type
primary antibodies
clone
M38, monoclonal
form
buffered aqueous solution
species reactivity
( Human), rabbit, ( Cat)
technique(s)
flow cytometry: suitable
isotype
IgG1
UniProt accession no.
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CD81(975)
General description
CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
Immunogen
MOLT-4 (human T-ALL cell line)
Biochem/physiol Actions
The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Physical form
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Preparation Note
Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Other Notes
The antibody solution should be gently mixed before use.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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