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SAB5200076

Sigma-Aldrich

Monoclonal Anti-KCND3 antibody produced in mouse

clone S75-41, 1 mg/mL, purified immunoglobulin

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Synonym(s):
Anti-Kcnd3, Anti-Kv4.3, Anti-Kv4.3 K+ channel, S75-41
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

S75-41, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 75 kDa

species reactivity

human, mouse, rat, Xenopus

concentration

1 mg/mL

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NP_113927.2

UniProt accession no.

Q9UK17

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Kcnd3(65195)

General description

The gene ID of the protein potassium voltage-gated channel subfamily D member 3 (KCND3) is 65195.

Specificity

Detects ~75 kDa in rat brain membrane preparations

Immunogen

Fusion protein amino acids 415-636 (cytoplasmic C-temrinus) of rat Kv4.3

Biochem/physiol Actions

Potassium voltage-gated channel subfamily D member 3 (KCND3) has an influence on the electrical activity of neurons concerned with gonadotropin-releasing hormone.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Armando Arroyo et al.
Reproductive sciences (Thousand Oaks, Calif.), 18(2), 136-144 (2010-09-24)
Regular and timely electrical activity of gonadotrophin-releasing hormone (GnRH) neurons accompanies the pulsatile release of GnRH that plays a central role in regulating fertility. Although transient outward A-type currents (I(A)) have been electrophysiologically identified in GnRH neurons, the molecular identity
Peng Zhong et al.
Journal of cardiovascular pharmacology, 70(4), 245-254 (2017-07-01)
Obesity/hyperlipidemia is closely related to both atrial and ventricular arrhythmias. CaMKII, a multifunctional serine/threonine kinase, has been involved in cardiac arrhythmias of different etiologies. However, its role in obesity/hyperlipidemia-related cardiac arrhythmia is unexplored. The aim of this was to determine

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