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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 28.5 kDa
species reactivity
mouse, human, rat
concentration
1 mg/mL
technique(s)
indirect immunofluorescence: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Aqp1(25240)
General description
Aquaporin 1 (AQP1) is expressed in the nervous system. The gene ID of the protein is 25240.
Immunogen
N-terminal peptide
Biochem/physiol Actions
Aquaporin 1 (AQP1) aids in transporting water across cell membranes. It also contributes to the migration and proliferation of pulmonary arterial smooth muscle cells.
Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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E Segura-Anaya et al.
Neuroscience, 285, 119-127 (2014-12-03)
Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-transporting proteins, which facilitate water movement across cell membranes in response to osmotic gradients. Several papers have studied the expression and function of the AQPs in the
The aquaporin 1 C-terminal tail is required for migration and growth of pulmonary arterial myocytes.
Ning Lai et al.
American journal of respiratory cell and molecular biology, 50(6), 1010-1020 (2013-12-18)
Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development of pulmonary hypertension. We previously demonstrated that aquaporin (AQP)1, a member of the water channel family of proteins, was expressed
Dieanira Erudaitius et al.
PloS one, 12(1), e0170442-e0170442 (2017-01-21)
Cancer cell toxicity to therapeutic H2O2 varies widely depending on cell type. Interestingly, it has been observed that different cancer cell types have varying peroxiporin expression. We hypothesize that variation in peroxiporin expression can alter cell susceptibility to therapeutic H2O2
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