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Merck
CN

SAB5200109

Anti-AQP1 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Synonym(s):

Anti-AQP1, Anti-Aquaporin 1, Anti-Water channel protein CHIP29

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-AQP1 antibody produced in rabbit, 1 mg/mL, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 28.5 kDa

species reactivity

mouse, human, rat

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: suitable
western blot: suitable

NCBI accession no.

NP_036910.1

UniProt accession no.

P29972

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rat ... Aqp1(25240)

Biochem/physiol Actions

Aquaporin 1 (AQP1) aids in transporting water across cell membranes. It also contributes to the migration and proliferation of pulmonary arterial smooth muscle cells.
Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Aquaporin 1 (AQP1) is expressed in the nervous system. The gene ID of the protein is 25240.

Immunogen

N-terminal peptide

Physical form

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
1112

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Ning Lai et al.
American journal of respiratory cell and molecular biology, 50(6), 1010-1020 (2013-12-18)
Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development of pulmonary hypertension. We previously demonstrated that aquaporin (AQP)1, a member of the water channel family of proteins, was expressed
E Segura-Anaya et al.
Neuroscience, 285, 119-127 (2014-12-03)
Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-transporting proteins, which facilitate water movement across cell membranes in response to osmotic gradients. Several papers have studied the expression and function of the AQPs in the
Dieanira Erudaitius et al.
PloS one, 12(1), e0170442-e0170442 (2017-01-21)
Cancer cell toxicity to therapeutic H2O2 varies widely depending on cell type. Interestingly, it has been observed that different cancer cell types have varying peroxiporin expression. We hypothesize that variation in peroxiporin expression can alter cell susceptibility to therapeutic H2O2

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