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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
RM261, monoclonal, recombinant monoclonal
Species reactivity:
human
Application:
IHC
Citations:
1
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM261, monoclonal, recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
immunoblotting: 1:1000-1:2000, immunohistochemistry: 1:1000-1:10,000
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr705)
Quality Level
Gene Information
human ... STAT3(6774)
Immunogen
Synthetic peptide corresponding to human Phospho-Stat3 (Tyr705)
Biochem/physiol Actions
This antibody reacts to human Stat3 only when phosphorylated at Tyr705. There is no cross-reactivity to stat3 without phosphorylation at Tyr705. This antibody may also react to mouse or rat Phospho-Stat3 (Tyr705), as predicted by immunogen homology.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Chengliang Yuan et al.
Journal of biochemical and molecular toxicology, 36(1), e22943-e22943 (2021-11-02)
Eriocitrin, a lemons flavanone, exhibits several biological properties, antiproliferative, and proapoptotic effects. However, its molecular mechanical action is not entirely clarified. Oxidative stress causes abnormal stimulation of signal transducer and activator of transcription 3 (STAT3) and c-Jun NH2-terminal kinase (JNK), p38
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