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Merck
CN

SAB5701227

Sigma-Aldrich

Anti-Gemin 2 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

rat, mouse, human

concentration

0.5 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... Gemin 2(8487)

General description

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Immunogen

Recombinant protein of human Gemin 2 .

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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