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Merck
CN

SAB5702003

[KO Validated]Anti-CD133 Antibody, clone 3Y4A5, Rabbit Monoclonal

Synonym(s):

PROM1, AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, prominin-1

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
3Y4A5, monoclonal
Application:
IHC, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

3Y4A5, monoclonal

form

liquid

mol wt

120 kDa

species reactivity

human

concentration

0.6 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

IPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQQGYQSLNDIPDRVQRQTTTVVA

UniProt accession no.

O43490

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CD133(8842)

General description

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 250-380 of human CD133 (O43490).

Application

WB, IHC

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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