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Merck
CN

SAB5702111

Anti-TSC2 Antibody, clone 7X2C6, Rabbit Monoclonal

Synonym(s):

LAM,PPP1R160,TSC4,TSC2,Tuberin,tuberin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

7X2C6, monoclonal

form

liquid

mol wt

200 kDa

species reactivity

human

concentration

0.52 mg/mL

technique(s)

immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

AKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TSC2(7249)

General description

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1700-1807 of human Tuberin (P49815).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB,IP

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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