SAB5702138
Anti-ANPRB/NRP2 Antibody, clone 1S1H1, Rabbit Monoclonal
Synonym(s):
NPR2, AMDM, ANPRB, ANPb, ECDM, GUC2B, GUCY2B, NPRB, NPRBi, SNSK, natriuretic peptide receptor 2
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1S1H1, monoclonal
Application:
WB
Citations:
-
color
colorless
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
1S1H1, monoclonal
form
liquid
mol wt
130 kDa
concentration
0.50 mg/mL
technique(s)
western blot: 1:500 - 1:2000
isotype
IgG
immunogen sequence
NLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNF
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ANPRB(4882)
species reactivity
human
General description
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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