SAB5702264
Anti-TIMP2 Antibody, clone 8R5Q2, Rabbit Monoclonal
Synonym(s):
TIMP2,CSC-21K,DDC8
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
8R5Q2, monoclonal
Application:
WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
8R5Q2, monoclonal
form
liquid
mol wt
22 kDa
species reactivity
African green monkey, rat, mouse, human
concentration
1.00 mg/mL
technique(s)
western blot: 1:500 - 1:1000
color
colorless
isotype
IgG
immunogen sequence
VSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGS
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TIMP2(7077)
General description
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Immunogen
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human TIMP2.
Application
WB
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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