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Merck
CN

SAB5702534

Sigma-Aldrich

[KO Validated]Anti-EGFR Antibody, clone 3J1E3, Rabbit Monoclonal

Synonym(s):

ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

3J1E3, monoclonal

form

liquid

mol wt

175 kDa

species reactivity

human

concentration

0.495 mg/mL

technique(s)

western blot: 1:100000 - 1:123500

color

colorless

isotype

IgG

immunogen sequence

SINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EGFR(1956)

General description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human EGFR (NP_005219.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Information

常规特殊物品
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