SAB5702573
Anti-RUNX1/2/3 Antibody, clone 6G5U2, Rabbit Monoclonal
Synonym(s):
AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6G5U2, monoclonal
Application:
WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
6G5U2, monoclonal
form
liquid
mol wt
45-55 kDa
Quality Level
Gene Information
human ... 2(864), 3(860), RUNX1(861)
concentration
0.28 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
LPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 354-453 of human RUNX1/2/3 (Q01196).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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