SAB5702641
Anti-MSH6 Antibody, clone 7M6T3, Rabbit Monoclonal
别名:
GTBP, GTMBP, HNPCC5, HSAP, p160
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
IF, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
7M6T3, monoclonal
form
liquid
mol wt
160 kDa
species reactivity
rat, human
concentration
0.43 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKM
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MSH6(2956)
General description
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSH6 (P52701).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC
存储类别
10 - Combustible liquids
wgk
WGK 1