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Merck
CN

SAB5702665

Anti-CCDC98 Antibody, clone 1J4E1, Rabbit Monoclonal

Synonym(s):

FAM175A, ABRA1, CCDC98, BRCA1-A complex subunit Abraxas

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1J4E1, monoclonal
Application:
IP, WB
Citations:
-
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

1J4E1, monoclonal

form

liquid

mol wt

50 kDa

species reactivity

human

concentration

0.33 mg/mL

technique(s)

immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

SCNYNHHLDVVDNLTLMVEHTDIPEASPASTPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGSSNQDKASKMSSPETDEEIEKMKGFGEYSRSPTF

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CCDC98(84142)

General description

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 310-409 of human CCDC98 (Q6UWZ7).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IP

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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