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Merck
CN

SAB5702823

Anti-α-Actin-1 (ACTA1) antibody

rabbit monoclonal, 8T8D0

Synonym(s):

ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, SHPM

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
Clone:
8T8D0, monoclonal
Technique(s):
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
Application:
IF, WB
Citations:
-

Key Documents

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Product Name

Anti-α-Actin-1 (ACTA1) Antibody, clone 8T8D0, Rabbit Monoclonal,

biological source

rabbit

material

colorless

clone

8T8D0, monoclonal

form

liquid

mol wt

42 kDa

concentration

0.8 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAP

UniProt accession no.

P68133

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... Actin(58)

species reactivity

human

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General description

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human α-Actin-1 (ACTA1) (P68133).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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