SAB5702849
Anti-LEF1 Antibody, clone 9I9T4, Rabbit Monoclonal
Synonym(s):
LEF-1, TCF10, TCF1ALPHA, TCF7L3
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
9I9T4, monoclonal
form
liquid
mol wt
30-50 kDa
species reactivity
mouse, mouse
concentration
0.28 mg/mL
technique(s)
immunofluorescence: 1:100 - 1:500
immunohistochemistry: 1:500 - 1:900
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
LADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHA
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... LEF1(51176)
General description
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LEF1 (Q9UJU2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC, IF/ICC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Regulatory Information
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