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Merck
CN

SAB5702922

Anti-ZNF259 Antibody, clone 10V1A2, Rabbit Monoclonal

Synonym(s):

ZPR1, ZNF259, ZPR1 zinc finger

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
10V1A2, monoclonal
Application:
IHC, WB
Citations:
-
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

10V1A2, monoclonal

form

liquid

mol wt

51 kDa

Quality Level

Gene Information

human ... ZNF259(8882)

concentration

0.38 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

DIRELVTKNPFTLGDSSNPGQTERLQEFSQKMDQIIEGNMKAHFIMDDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 360-459 of human ZNF259 (O75312).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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