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Merck
CN

SAB6010085

Sigma-Aldrich

Anti-phospho-JUN (S63) antibody, clone 4A11, Rabbit Monoclonal

recombinant, expressed in HEK293F cells

Synonym(s):

Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

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About This Item

UNSPSC Code:
12352203

Key Documents

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recombinant

expressed in HEK 293 F cells

Quality Level

100

conjugate

unconjugated

antibody product type

primary antibodies

clone

4A11, recombinant monoclonal

form

liquid

mol wt

150 kDa

purified by

affinity chromatography

species reactivity

human

concentration

0.5mg/ml

technique(s)

ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200

isotype

IgG

UniProt accession no.

P05412

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

phosphorylation (pSer63)

General description

Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).

Immunogen

A synthesized peptide derived from human Phospho-JUN (S63)

Physical form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preparation Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Other Notes

LT-pS-PD

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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