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Merck
CN

SAB6012258

Anti Ribonuclease Antibody, clone 24GB1575, Rabbit Monoclonal

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clone 24GB1575, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

PRCA1, RNS4, RNase L

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
24GB1575, recombinant monoclonal
Application:
WB
Citations:
-

Key Documents

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biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB1575, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

84 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... RNASEL(6041)

sustainability

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concentration

0.39 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000135828

NCBI accession no.

NP_066956.1

UniProt accession no.

Q05823

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. The protein is involved in innate immunity and is active against multiple RNA viruses, including the influenza and SARS-CoV-2 viruses. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Nov 2021]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 550-741 of human RNase L [NP_066956.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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