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Merck
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SAB6012458

KD-Validated Anti TARBP2 Antibody, clone 24GB2425, Rabbit Monoclonal

newenhanced validation

clone 24GB2425, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

LOQS, TRBP, TRBP1, TRBP2, Trbp

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB2425, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

39 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.8 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000139546

NCBI accession no.

NP_599150.1

UniProt accession no.

Q15633

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TARBP2(6895)

General description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 230-280 of human TRBP [NP_599150.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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