SBR00045
Gentamicin-Amphotericin B
Ready Made Solution, Gentamicin 25mg/mL and Amphotericin B 125µg/mL
Synonym(s):
Gentamicin-Amphotericin B Ready Made Solution
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About This Item
NACRES:
NA.76
UNSPSC Code:
51281607
Quality Level
form
ready-to-use solution
specific activity
Antibacterial and antifungal
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, fungi, mycoplasma, yeast
mode of action
cell membrane | interferes, protein synthesis | interferes
storage temp.
−20°C
Related Categories
General description
Gentamicin-Amphotericin B is an aqueous based stable formulation, intended to eradicate sensitive bacterial and fungal infections. Gentamicin is an aminoglycoside class antibiotic inhibiting the protein synthesis preventing the growth of gram positive and gram-negative bacteria. Amphotericin B is a well-known polyene antifungal compound used in cell culture. The Gentamicin-Amphotericin B mixture is especially usable for cell culture applications and as part of viral transfer media (VTM).
Other Notes
- The Gentamicin-Amphotericin B mixture is composed from Gentamicin 25mg/ml and Amphotericin B 125 µg/mL.
- The working concentrations according to CDC SOP# DSR-052-05 are 100 µg/mL for Gentamicin and 0.5 µg/mL for Amphotericin B.
- 2mL Gentamicin-Amphotericin B stock mixture is sufficient to prepare 500 mL working concentration.
- The product is packed under aseptic conditions.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Criticality of in-house preparation of viral transport medium in times of shortage during COVID-19 pandemic
Petersen, Jeffrey, Sharvari Dalal, et al
Laboratory Medicine, 52, no. 2, e39-e45 (2021)
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