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About This Item
Empirical Formula (Hill Notation):
C177H279N53O48
Molecular Weight:
3917.44
UNSPSC Code:
12352209
NACRES:
NA.32
Product Name
[Nle8,18,Tyr34]-PTH 3-34 bovine,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥85%
storage condition
protect from light
storage temp.
−20°C
Application
Parathyroid hormone (PTH) is an 84 amino acid hormone involved in calcium regulation in counteraction to calcitonin. PTH regulates serum phosphate levels and vitamin D biosynthesis. N-terminal peptides of PTH are used to elicit and study a wide variety of responses in target cells. PTH N-terminal peptides include: PTH (1-34); [Nle8,18,Tyr34]-PTH 1-34; PTH (2-34); [Nle8,18,Tyr34]-PTH (2-34); PTH (3-34); [Nle8,18,Tyr34]-PTH (3-34); PTH (4-34) and PTH (5-34).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Estelle N Bianchi et al.
Bone, 45(4), 716-725 (2009-06-30)
Interaction of the cytoplasmic adaptor molecule beta-arrestin2 with the activated parathyroid hormone (PTH)/PTHrP receptor inhibits G protein mediated signaling and triggers MAPKs signaling. In turn, the effects of both intermittent (i.) and continuous (c.) PTH on bone are altered in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SCP0234-500UG | 04061833025499 |
| SCP0234-1MG | 04061823600804 |
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