SML1483
Ogerin negative control
≥98% (HPLC)
Synonym(s):
3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
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About This Item
Empirical Formula (Hill Notation):
C17H17N5O
CAS Number:
Molecular Weight:
307.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1
InChI
1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
InChI key
RVKAHYFWSKSSQQ-UHFFFAOYSA-N
Biochem/physiol Actions
Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.
Ogerin negative control is a structurally similar analog of ogerin.
Other Notes
The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1483-5MG | 04061832983530 |
| SML1483-25MG | 04061832983523 |
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