SML2537
NSAH
≥98% (HPLC)
别名:
2-Hydroxy-benzoic acid (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
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关于此项目
经验公式（希尔记法）:
C18H14N2O3
化学文摘社编号:
分子量:
306.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC=CC=C1C(N/N=C/C2=C(C=CC=C3)C3=CC=C2O)=O
InChI
1S/C18H14N2O3/c21-16-8-4-3-7-14(16)18(23)20-19-11-15-13-6-2-1-5-12(13)9-10-17(15)22/h1-11,21-22H,(H,20,23)/b19-11+
InChI key
ZZSJOLDICPVVAV-YBFXNURJSA-N
Biochem/physiol Actions
NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells.
cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable