SML2543
KA-11
≥98% (HPLC)
别名:
1-[1-Methyl-2-oxo-2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2,5-pyrrolidinedione
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CC(N1C(CCC1=O)=O)C(N(CC2)CCN2C3=CC=CC(C(F)(F)F)=C3)=O
InChI
1S/C18H20F3N3O3/c1-12(24-15(25)5-6-16(24)26)17(27)23-9-7-22(8-10-23)14-4-2-3-13(11-14)18(19,20)21/h2-4,11-12H,5-10H2,1H3
InChI key
DWLZEEPJISTVEO-UHFFFAOYSA-N
Biochem/physiol Actions
Broad-spectrum anticonvulsant
KA-11 is a broad-spectrum anticonvulsant hybrid molecule that joins the chemical fragments of well-known anti-epileptic drugs such as ethosuximide, levetiracetam, and lacosamide. KA-11 was shown to have antiepileptogenic and antinociceptive properties in animal models. Its mechanism of action is believed to involve influence on the neuronal voltage-sensitive sodium and L-type calcium channels.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable