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SRP0448

BRD1 (561-668) His tag human

Name: BRD1 (561-668) His tag human
Brand: SIGMA

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

BRL, Bromodomain containing 1

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About This Item

NACRES:

NA.32

UNSPSC Code:

12352200

Biological source:

human

Recombinant:

expressed in E. coli

Assay:

≥90% (SDS-PAGE)

Form:

aqueous solution

Mol wt:

13.7 kDa

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biological source

human

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

13.7 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_014577

UniProt accession no.

O95696

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRD1(23774)

General description

Human Bromodomain containing 1, also known as BRD1 and BRL (GenBank Accession No. NM_014577) amino-acids 561 – 668 with N-terminal HIS-tag, MW = 13.7 kDa, expressed in an E. coli expression system.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

3101020216

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Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder.

J E Severinsen et al.

Molecular psychiatry, 11(12), 1126-1138 (2006-08-23)

Linkage studies suggest that chromosome 22q12-13 may contain one or more shared susceptibility genes for schizophrenia (SZ) and bipolar affective disorder (BPD). In a Faeroese sample, we previously reported association between microsatellite markers located at 22q13.31-qtel and both disorders. The

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

Yuta Mishima et al.

Blood, 118(9), 2443-2453 (2011-07-15)

The histone acetyltransferases (HATs) of the MYST family include TIP60, HBO1, MOZ/MORF, and MOF and function in multisubunit protein complexes. Bromodomain-containing protein 1 (BRD1), also known as BRPF2, has been considered a subunit of the MOZ/MORF H3 HAT complex based

Global Trade Item Number

SKU	GTIN
SRP0448-100UG	04061832782560

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