SRP0487
Bromodomain Non-Acetylated Ligand 2
≥95% (HPLC)
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
Assay
≥95% (HPLC)
form
aqueous solution
mol wt
2723.2 kDa
packaging
pkg of 5 mL
shipped in
dry ice
storage temp.
−20°C
General description
The Bromodomain Non-acetylated Ligand 2 is peptide histone H3 (1-21). It contains an C-terminal GG linker, followed by a biotinylated Lys. Bromodomains function as acetyl-lysine binding domains, and bromodomain/acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription. This peptide is suitable for use as a negative control for several bromodomains including ATAD2 and BAZ2B.
Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Pil-Hoon Park et al.
American journal of physiology. Gastrointestinal and liver physiology, 289(6), G1124-G1136 (2005-08-06)
Ethanol treatment increases gene expression in the liver through mechanisms that are not clearly understood. Histone acetylation has been shown to induce transcriptional activation. We have investigated the characteristics and mechanisms of ethanol-induced histone H3 acetylation in rat hepatocytes. Immunocytochemical
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