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Merck
CN

SRP4757

GDF-3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym(s):

Growth Diffrentiation Factor-3, Growth/Differentiation Factor-3

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Technical Service
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biological source

human

recombinant

expressed in E. coli

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

form

lyophilized

mol wt

~13 kDa

packaging

pkg of 20 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GDF3(9573)

General description

GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains

Physical form

Sterile filtered and lyophilized with no additives.

Preparation Note

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.


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Global Trade Item Number

SKUGTIN
SRP4757-20UG04061837227516