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Merck
CN

SRP6305

Lactalbumin from human milk

≥95% (SDS-PAGE)

Synonym(s):

LYZL7

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352202
Biological source:
human milk
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized
Mol wt:
14 kDa
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biological source

human milk

assay

≥95% (SDS-PAGE)

form

lyophilized

mol wt

14 kDa

packaging

pkg of 5 mg

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... LYZL7(3906)

General description

α-Lactalbumin is an important whey protein in cow′s milk, and is also present in the milk of many other mammalian species. In primates, α-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (β4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, α-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme′s affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase.

Physical form

Lyophilized from de-ionized water.

Preparation Note

Use deionized water

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

高风险级别生物产品--人源产品
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