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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Biological source:
human milk
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized
Mol wt:
14 kDa
biological source
human milk
assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
14 kDa
packaging
pkg of 5 mg
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... LYZL7(3906)
General description
α-Lactalbumin is an important whey protein in cow′s milk, and is also present in the milk of many other mammalian species. In primates, α-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (β4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, α-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme′s affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase.
Physical form
Lyophilized from de-ionized water.
Preparation Note
Use deionized water
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
高风险级别生物产品--人源产品
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