T2330
TSSK2, active, GST tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
DGS-G, FLJ38613, SPOGA2, STK22B
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Specific activity:
116-156 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
Quality Level
recombinant
expressed in baculovirus infected Sf9 cells
product line
PRECISIO® Kinase
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
116-156 nmol/min·mg
mol wt
~66 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... TSSK2(23617)
Application
Human TSSK2, active, GST tagged, may be used to study testis-specific serine/threonine-protein kinase that plays a pivotal role in spermiogenesis.
Biochem/physiol Actions
TSSK2, a protein that belongs to Testis-specific serine/threonine-protein kinase family facilitates the spermatid development. It also has a crucial role in the formation and function of sperm cells in the mouse. Mutation in TSSK2 Gene leads to Human Spermatogenesis Impairment.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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S Nayak et al.
Mechanisms of development, 74(1-2), 171-174 (1998-07-04)
Previously we identified two intronless serine-threonine kinase genes (Tsk1 and Tsk2) located 3 kb apart on mouse chromosome 16 (Galili, N., Baldwin, H.S., Lund, J., Reeves, R., Gong, W., Wang, Z., Roe, B.A., Emanuel, B.S., Nayak, S., Mickanin, C., Budraf
Zhonglin Hao et al.
Molecular human reproduction, 10(6), 433-444 (2004-03-27)
Two members of the human testis-specific serine/threonine (Ser/Thr) kinase family, TSSK 1 and TSSK 2, were cloned and sequenced from a human testis adaptor-ligated cDNA library using a PCR strategy. Within the cDNA, open reading frames (ORF) were defined encoding
Hao Zhang et al.
Journal of andrology, 31(4), 388-392 (2009-11-21)
Tssk2, a member of the testis-specific serine/threonine kinase (TSSK) family, is expressed predominantly in the testis and is crucial for the formation and function of sperm cells in the mouse. Targeted deletion of Tssk1 and Tssk2 in male chimeric mice
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