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Merck
CN

U6135

Ubiquitin-Specific Protease 8 human

recombinant, expressed in Sf9 cells, ≥70% (SDS-PAGE)

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关于此项目

NACRES:
NA.77
UNSPSC Code:
12352204
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in Sf9 cells
Concentration:
≥0.10 mg/mL protein (Bradford)
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recombinant

expressed in Sf9 cells

Quality Segment

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

128 kDa

concentration

≥0.10 mg/mL protein (Bradford)

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

General description

Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, amino-acids 2-1118 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biochem/physiol Actions

Expression of ubiquitin-specific protease 8 (USP8) in mice is critical for proper expression and stability of several growth factor receptors including epidermal growth factor receptor. However, USP8 was shown to degrade chemokine receptor 4.

Physical form

Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 ng/μl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0.


存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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