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Merck
CN

WH0011138M2

Monoclonal Anti-TBC1D8 antibody produced in mouse

clone 1A12, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-AD3, Anti-HBLP1, Anti-TBC1 domain family, member 8 (with GRAM domain), Anti-VRP

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1A12, monoclonal
Application:
ELISA (i), IF, WB
Citations:
3

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1A12, monoclonal

form

buffered aqueous solution

species reactivity

rat, mouse, human

technique(s)

immunofluorescence: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

NM_007063

UniProt accession no.

O95759

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... TBC1D8(11138)

General description

TBC1 domain family member 8 (TBC1D8) gene is located on human chromosome 2q11.2.

Immunogen

TBC1D8 (NP_008994, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTAGRMFASDSYICFASREDGCCKIILPLREVVSIEKME

Biochem/physiol Actions

TBC1 domain family member 8 (TBC1D8) is involved in blood coagulation and circulation. It functions as a GTPase-activating protein for the Rab family. The protein is associated with membrane trafficking.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
07124-1A12

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Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
Jung J, et al.
eLife, 6(3), e23063-e23063 (2017)
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits
Hsu YH, et al.
PLoS Genetics, 6(6), e1000977-e1000977 (2010)
Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing
Ai H, et al.
Nature Genetics, 47(3), 217-217 (2015)

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