14022AST
Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns
L × I.D. 10 cm × 4.6 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
10 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
teicoplanin aglycone phase
Pore size:
100 Å
Matrix:
High-purity silica gel particle platform, fully porous particle
Product Name
Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L63
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature, 241 bar pressure (3500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
10 cm × 4.6 mm
matrix
High-purity silica gel particle platform, fully porous particle
matrix active group
teicoplanin aglycone phase
particle size
5 μm
pore size
100 Å
operating pH range
3.0-6.8
separation technique
chiral
General description
The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.
- Bonded phase: Teicoplanin aglycone
- Operating pH range: 3.0 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Julia Koidl et al.
Journal of biochemical and biophysical methods, 70(6), 1254-1260 (2007-11-06)
This paper deals with the chiral separation of triiodothyronine (T3) and thyroxine (T4) by HPLC and micro-HPLC. The separation of T3 and T4 is of great pharmaceutical and clinical interest, since the enantiomers exhibit different pharmacological activities. The HPLC measurements
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14022AST | 04061833513965 |