product line
TOYOPEARL®
form
slurry
mol wt
2000 - 750,000
packaging
bottle of 25 mL
manufacturer/tradename
Tosoh 21887
parameter
≤50% organic solvent, 3 bar max. pressure
technique(s)
LPLC: suitable
matrix
hydroxylated methacrylic polymer
matrix active group
phenyl phase
particle size
65 μm
operating pH
1-13
capacity
55 g/L±10 adsorption capacity (lysozyme)
separation technique
hydrophobic interaction (HIC)
General description
Toyopearl Phenyl-600 resin has the middle hydrophobicity of the five HIC ligands offered by Tosoh Bioscience. Its pore size has been optimized for the chromatography of monoclonal antibodies and it is typically used in an intermediate or polishing step. It is a very high recovery and high dynamic capacity resin for both large and small proteins. When used as the polishing step up to an extra 5% yield may be seen compared to other Phenyl resins. To see other products optimized for HIC purification of mAbs please see Toyopearl PPG-600 and Toyopearl Butyl-600 resins.
Features and Benefits
Clean in place with 0.5 M NaOH or 0.1 M HCl.
Physical form
72% (v/v) slurry in 20% (v/v) ethanol
Shipped in 20% (v/v) ethanol.
Legal Information
Toyopearl is a registered trademark of Tosoh Corporation
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signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 3