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Merck
CN

CRM01373

Tebufenozide

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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About This Item

Empirical Formula (Hill Notation):
C22H28N2O2
CAS Number:
Molecular Weight:
352.47
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
7822297
MDL number:
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SMILES string

CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C

InChI key

QYPNKSZPJQQLRK-UHFFFAOYSA-N

InChI

1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)

grade

certified reference material, TraceCERT®

product line

TraceCERT®

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Quality Level

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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Tebufenozide is a non-steroidal ecdysone agonist herbicide that belongs to the class of diacylhydrazines. It interacts with the steroidal receptors in lepidopterans larvae and produces lethal molting.
Tebufenozide was allowed for use in the European Union as a plant protection agent as per the Commission Implementing Directive 2011/60/EU of 23rd May 201, repealing Directive 91/414/EEC. A maximum residue limit (MRL) of 2 mg/kg and 0.05 mg/kg is set for the presence of tebufenozide in fresh/frozen fruits and tree nuts respectively according to the Reg. (EU) 2021/1807.

Application

It is intended to be used as a certified reference material (CRM) for calibration in chromatography and other analytical techniques.
Tebufenozide certified reference material (CRM) may also find the following uses:

  • Analysis of trifloxystrobin, tebufenozide, and halofenozide by Micellar electrokinetic capillary chromatography (MEKC) in tomato, celery, and apple juice samples
  • Measurement of the residue levels of tebufenozide in cabbage and soil by reversed-phase high-performance liquid chromatography (HPLC)
  • Determination of four diacylhydrazine insecticide residues in apple, grape, cucumber, tomato, and spinach samples by QuEChERS method using ultra-performance liquid chromatography coupled with tandem mass spectrometry
  • Development and validation of a multi-residual analytical method, based on SPE followed by LC-MS for the simultaneous estimation of 14 pesticides in surface and groundwaters
  • Multi-residue analysis of 200 pesticides and pesticide metabolites in honeybees by gas and liquid chromatography coupled with tandem mass spectrometry

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

农药列管产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of trifloxystrobin, tebufenozide, and halofenozide in foods by micellar electrokinetic capillary chromatography
Araujo L, et al.
Analytical Letters, 2340-2348 null
Hongfang Lin et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 120, 64-70 (2018-07-01)
Tebufenozide, a newly-developed nonsteroidal ecdysone agonist, is in pre-regulation phase (before approval for use) on stem lettuce in China. Aiming at the safe application of tebufenozide, the dissipation and terminal residue trials on stem lettuce were performed under good agricultural
Jie Liu et al.
Ecotoxicology and environmental safety, 134P1, 204-212 (2016-09-17)
The novel nonsteroidal ecdysone agonist tebufenozide is capable of controlling a wide range of lepidopteran pests. However its intensive use in vegetables has raised concerns towards the safety of food and environment. Here, we developed an easy and reliable method
Muhammad Fiaz et al.
Chemosphere, 212, 337-345 (2018-08-27)
The velvetbean caterpillar, Anticarsia gemmatalis Hübner (Lepidoptera: Noctuidae), is an important soybean pest in the Americas. Tebufenozide, a novel nonsteroidal ecdysone agonist is used to control this pest. Bioassays were conducted to assess tebufenozide toxicity and their ultrastructural effects on
Determination of tebufenozide and methoxyfenozide residues in vegetables using liquid chromatography-electrospray tandem mass spectrometry
Lin D, et al.
Chinese Journal of Analytical Chemistry, 87-90 null

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