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PHR9070

Supelco

Favipiravir

certified reference material, TraceCERT®

Synonym(s):
6-Fluoro-3-hydroxy-2-pyrazinecarboxamide, T705, Avigan, T-705, 6-fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide
Empirical Formula (Hill Notation):
C5H4FN3O2
CAS Number:
Molecular Weight:
157.10
MDL number:

Quality Level

grade

certified reference material
TraceCERT®

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

storage temp.

−20°C

SMILES string

FC1=CNC(C(C(N)=O)=N1)=O

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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

Biochem/physiol Actions

Favipiravir (T-705) is an inhibitor of viral RNA polymerase. In cells, the comound is converted to T-705-4-ribofuranosyl-5-triphosphate, which selectively targets the viral polymerase without affecting mammalian RNA or DNA polymerases. Favipiravir inhibits replication of inluenza viruse A, B and C with IC50 values between 0.013 and 0.48 mM. The compound protects mice from lethal-dose infections of wild type and neuraminidase inhibitor-resistant strains of H5N1 viruses, Favipiravir has been found to have activity against many viruses including flavi-, alpha-, filo-, bunya-, arena-, noro-, and of other RNA viruses, and is already used off-label for Ebola and Lassa virus.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Muta. 2 - Repr. 2

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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