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Showing 1-30 of 130 results for "PHR1056" within Papers
Juliane Krebes et al.
International journal of medical microbiology : IJMM, 304(8), 1135-1146 (2014-09-15)
The human gastric pathogen Helicobacter pylori is characterised by a high mutation rate and frequent recombination during mixed infection, which result in extensive genetic diversity and rapid allelic diversification. Mixed infections are believed to be much more common in regions
Min Zhu et al.
Journal of leukocyte biology, 96(2), 349-357 (2014-05-02)
Individuals with T2D and PD suffer significantly from the ability of one disease to intensify the other. Disease-associated inflammation is one mechanism thought to fuel this pathogenic feed-forward loop. Several lines of evidence indicate that proinflammatory B cells promote T2D
Shah M Rashed et al.
Journal of medical microbiology, 61(Pt 12), 1736-1745 (2012-09-15)
Vibrio cholerae O1 biotype El Tor (ET), causing the seventh cholera pandemic, was recently replaced in Bangladesh by an altered ET possessing ctxB of the Classical (CL) biotype, which caused the first six cholera pandemics. In the present study, V.
Florence M Mutua et al.
The Cochrane database of systematic reviews, 8(8), CD007933-CD007933 (2012-08-17)
Genital ulcer disease by virtue of disruption of the mucosal surfaces may enhance HIV acquisition. Genital ulcer disease treatment with resolution of the ulcers may therefore contribute in reducing the sexual acquisition of HIV. To determine the effects of treatment
Astrid Bienert-Zeit et al.
American journal of veterinary research, 76(4), 318-327 (2015-03-31)
To monitor concentrations of sulfadimidine in the paranasal sinus mucosa (PSM) of unsedated horses following IV administration of trimethoprim-sulfadimidine via in vivo microdialysis. 10 healthy adult horses. Concentric microdialysis probes were implanted into the subepithelial layers of the frontal sinus
Matthew Di Rago et al.
Forensic science international, 243, 35-43 (2014-05-06)
The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing.
Mohamed A Saleh et al.
The Journal of clinical investigation, 125(3), 1189-1202 (2015-02-11)
The lymphocyte adaptor protein LNK (also known as SH2B3) is primarily expressed in hematopoietic and endothelial cells, where it functions as a negative regulator of cytokine signaling and cell proliferation. Single-nucleotide polymorphisms in the gene encoding LNK are associated with
Emily A Snavely et al.
Pathogens and disease, 71(3), 336-351 (2014-05-20)
The secreted Chlamydia protease CPAF cleaves a defined set of mammalian and Chlamydia proteins in vitro. As a result, this protease has been proposed to modulate a range of bacterial and host cellular functions. However, it has recently come into
Comparison of trimethoprim molecularly imprinted polymers in bulk and in sphere as the sorbent for solid-phase extraction and extraction of trimethoprim from human urine and pharmaceutical tablet and their determination by high-performance liquid chromatography
Hu SG, et al.
Analytica Chimica Acta, 537(1-2), 215-222 (2005)
E Van Duijkeren et al.
Journal of veterinary pharmacology and therapeutics, 17(1), 64-73 (1994-02-01)
The indications for use, side-effects, and pharmacokinetic parameters of trimethoprim, sulfonamides and their combinations in the horse are reviewed. Trimethoprim/sulfonamide (TMPS) combinations are used for the treatment of various diseases caused by gram-positive and gram-negative bacteria, including infections of the
Stéphanie Romand et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63, 14-21 (2014-07-06)
A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated capillary in aqueous medium and
Do-Won Jeong et al.
International journal of food microbiology, 188, 108-115 (2014-08-12)
To select starters for jeotgal, a traditional Korean high-salt-fermented seafood, the safety and technological properties of its predominant bacteria isolates, which were identified as Staphylococcus equorum, were assessed. Among the 185 S. equorum isolates from jeotgal, 126 ampicillin-sensitive strains were
Trimethoprim.
Nursing times, 101(5), 31-31 (2005-03-01)
Ganna Fedorova et al.
Chemosphere, 111, 55-60 (2014-07-07)
In this study, the stability of 124 target analytes in influent and effluent wastewater samples during short-term (4°C) and long-term (-18°C) storage was assessed. The most common storage scenario was considered, in which samples were frozen immediately after sampling without
Xin Yang et al.
Environmental science and pollution research international, 20(8), 5864-5875 (2013-04-24)
The occurrence and fate of eight PPCPs was studied in river waters from upstream to downstream of the three rivers in the Pearl River Delta, China. The correlations of PPCP levels and water quality parameters were also investigated. The analytes
Mayu Kamimura et al.
Bioscience, biotechnology, and biochemistry, 78(3), 438-447 (2014-07-19)
Protein kinases are key regulators of cell function that constitute one of the largest and most functionally diverse gene families. We developed a novel assay system, based on the bimolecular fluorescence complementation (BiFC) technique in Escherichia coli, for detecting transient
Wendy Itzel Escobedo Hinojosa et al.
Journal of ethnopharmacology, 155(2), 1156-1163 (2014-06-28)
The root barks of Hippocratea celastroides have been used for decades in Mexican traditional medicine to treat gastritis and ulcers. To investigate the anti-Helicobacter pylori, gastroprotective, anti-inflammatory, and cytotoxic activities of methanolic extracts obtained from the leaves, stems, and root
Naoko Hara et al.
Journal of immunology (Baltimore, Md. : 1950), 189(8), 3805-3814 (2012-09-19)
Microbes were hypothesized to play a key role in the progression of type 1 diabetes (T1D). We used the LEW1.WR1 rat model of Kilham rat virus (KRV)-induced T1D to test the hypothesis that the intestinal microbiota is involved in the
Arif Hussain et al.
Antimicrobial agents and chemotherapy, 58(12), 7240-7249 (2014-09-24)
In view of the epidemiological success of CTX-M-15-producing lineages of Escherichia coli and particularly of sequence type 131 (ST131), it is of significant interest to explore its prevalence in countries such as India and to determine if antibiotic resistance, virulence
Concentration evolution of pharmaceutically active compounds in raw urban and industrial wastewater.
Dolores Camacho-Muñoz et al.
Chemosphere, 111, 70-79 (2014-07-07)
The distribution of pharmaceutically active compounds in the environment has been reported in several works in which wastewater treatment plants have been identified as the main source of these compounds to the environment. The concentrations of these compounds in influent
Irina Amorim et al.
Helicobacter, 19(4), 249-259 (2014-04-03)
The gastric mucosa of dogs is often colonized by non-Helicobacter pylori helicobacters (NHPH), while H. pylori is the predominant gastric Helicobacter species in humans. The colonization of the human gastric mucosa by H. pylori is highly dependent on the recognition
Laurel K Dodgen et al.
Environmental pollution (Barking, Essex : 1987), 198, 144-153 (2015-01-17)
The reuse of treated wastewater for agricultural irrigation in arid and hot climates where plant transpiration is high may affect plant accumulation of pharmaceutical and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs). In this study, carrot, lettuce, and
Magda Targa Martins et al.
Talanta, 129, 374-383 (2014-08-17)
In routine laboratory work, screening methods for multiclass analysis can process a large number of samples in a short time. The main challenge is to develop a methodology to detect as many different classes of residues as possible, combined with
Umayal Lakshmanan et al.
Combinatorial chemistry & high throughput screening, 17(9), 790-803 (2014-10-21)
Melioidosis is a serious emerging endemic infectious disease caused by Burkholderia pseudomallei, a gram-negative pathogen. Septicemic melioidosis has a mortality rate of 50% even with treatment. Like other gram-negative bacteria, B. pseudomallei is resistant to a number of antibiotics and
M Stephan-Güldner
Journal of chemotherapy (Florence, Italy), 5(6), 400-410 (1993-12-01)
The toxicology and safety pharmacology of brodimoprim (Ro 10-5970), a new dihydrofolate reductase inhibitor for antimicrobial chemotherapy, are reported. The toxicity is compared to trimethoprim and other dihydrofolate reductase inhibitors of the trimethoprim type. In safety pharmacological tests brodimoprim showed
Alia Ungurean et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 52-58 (2012-12-12)
Structural investigations by different vibrational spectroscopic methods: FTIR, FT-Raman and surface-enhanced Raman scattering (SERS) spectroscopy, as well as density functional theory (DFT) calculations were performed on trimethoprim (5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine). A reliable assignment of vibrational IR, Raman and SERS bands was possible
A Burian et al.
Pharmacology, 90(5-6), 281-287 (2012-10-06)
Although major impairment of activity at lower pH values has been reported for fluoroquinolones, acidification is a widely recommended practice for the prophylaxis and treatment of uncomplicated urinary tract infections (UTIs). Until now, there is little evidence for the influence
A Romano et al.
Physiology & behavior, 136, 55-62 (2014-05-08)
Chronic exposure to a diet rich in fats changes the gastrointestinal milieu and alters responses to several signals involved in the control of food intake. Oleoylethanolamide (OEA) is a gut-derived satiety signal released from enterocytes upon the ingestion of dietary
Anwar Anwar-Mohamed et al.
Toxicology letters, 230(3), 382-392 (2014-08-17)
Acquired cardiac long QT syndrome (LQTS) is a frequent drug-induced toxic event that is often caused through blocking of the human ether-á-go-go-related (hERG) K(+) ion channel. This has led to the removal of several major drugs post-approval and is a
R W Han et al.
Food chemistry, 181, 119-126 (2015-03-22)
A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). One milliliter of raw milk was diluted with 0.5 mL water and 3 mL acetonitrile
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